diff --git a/lib/v8.js b/lib/v8.js
index c0d4074aac21d5..d2c55d50002c70 100644
--- a/lib/v8.js
+++ b/lib/v8.js
@@ -47,6 +47,13 @@ const {
   Serializer,
   Deserializer,
 } = internalBinding('serdes');
+const {
+  DOMException,
+} = internalBinding('messaging');
+const {
+  messaging_clone_symbol,
+  messaging_deserialize_symbol,
+} = internalBinding('symbols');
 const {
   namespace: startupSnapshot,
 } = require('internal/v8/startup_snapshot');
@@ -381,6 +388,8 @@ function arrayBufferViewIndexToType(index) {
   return undefined;
 }
 
+const kDOMExceptionHostObjectTag = 14;
+
 class DefaultSerializer extends Serializer {
   constructor() {
     super();
@@ -395,6 +404,14 @@ class DefaultSerializer extends Serializer {
    * @returns {void}
    */
   _writeHostObject(abView) {
+    // Route DOMException through the same hooks used by structuredClone
+    if (abView instanceof DOMException) {
+      const { data } = abView[messaging_clone_symbol]();
+      this.writeUint32(kDOMExceptionHostObjectTag);
+      this.writeValue(data);
+      return;
+    }
+
     // Keep track of how to handle different ArrayBufferViews. The default
     // Serializer for Node does not use the V8 methods for serializing those
     // objects because Node's `Buffer` objects use pooled allocation in many
@@ -426,6 +443,14 @@ class DefaultDeserializer extends Deserializer {
    */
   _readHostObject() {
     const typeIndex = this.readUint32();
+    // Route DOMException through the same hooks used by structuredClone
+    if (typeIndex === kDOMExceptionHostObjectTag) {
+      const data = this.readValue();
+      const domException = new DOMException();
+      domException[messaging_deserialize_symbol](data);
+      return domException;
+    }
+
     const ctor = arrayBufferViewIndexToType(typeIndex);
     const byteLength = this.readUint32();
     const byteOffset = this._readRawBytes(byteLength);
diff --git a/src/node_serdes.cc b/src/node_serdes.cc
index 00fcd4b6afccce..d9e192fd78ba66 100644
--- a/src/node_serdes.cc
+++ b/src/node_serdes.cc
@@ -37,6 +37,8 @@ class SerializerContext : public BaseObject,
 
   ~SerializerContext() override = default;
 
+  bool HasCustomHostObject(Isolate* isolate) override { return true; }
+  Maybe<bool> IsHostObject(Isolate* isolate, Local<Object> object) override;
   void ThrowDataCloneError(Local<String> message) override;
   Maybe<bool> WriteHostObject(Isolate* isolate, Local<Object> object) override;
   Maybe<uint32_t> GetSharedArrayBufferId(
@@ -145,6 +147,28 @@ Maybe<uint32_t> SerializerContext::GetSharedArrayBufferId(
   return id->Uint32Value(env()->context());
 }
 
+Maybe<bool> SerializerContext::IsHostObject(Isolate* isolate,
+                                            Local<Object> object) {
+  Local<Object> per_context_bindings;
+  Local<Value> domexception_ctor_val;
+  if (!GetPerContextExports(env()->context()).ToLocal(&per_context_bindings) ||
+      !per_context_bindings
+           ->Get(env()->context(),
+                 FIXED_ONE_BYTE_STRING(env()->isolate(), "DOMException"))
+           .ToLocal(&domexception_ctor_val) ||
+      !domexception_ctor_val->IsFunction()) {
+    return Just(object->InternalFieldCount() != 0);
+  }
+
+  bool is_domexception = false;
+  if (!object
+           ->InstanceOf(env()->context(), domexception_ctor_val.As<Function>())
+           .To(&is_domexception)) {
+    return Nothing<bool>();
+  }
+  return Just(is_domexception || object->InternalFieldCount() != 0);
+}
+
 Maybe<bool> SerializerContext::WriteHostObject(Isolate* isolate,
                                                Local<Object> input) {
   Local<Value> args[1] = { input };
diff --git a/test/parallel/test-v8-serdes-domexception.js b/test/parallel/test-v8-serdes-domexception.js
new file mode 100644
index 00000000000000..233e6511611118
--- /dev/null
+++ b/test/parallel/test-v8-serdes-domexception.js
@@ -0,0 +1,30 @@
+'use strict';
+
+require('../common');
+const assert = require('node:assert');
+const { serialize, deserialize } = require('node:v8');
+
+// Simple case, should preserve message/name/stack like structuredClone
+{
+  const e = AbortSignal.abort().reason;
+
+  const cloned = deserialize(serialize(e));
+
+  assert(cloned instanceof DOMException);
+  assert.strictEqual(cloned.name, e.name);
+  assert.strictEqual(cloned.message, e.message);
+
+  assert.strictEqual(typeof cloned.stack, 'string');
+  assert(cloned.stack.includes(e.name));
+}
+
+// Nested case
+{
+  const e = AbortSignal.abort().reason;
+  const obj = { e };
+
+  const clonedObj = deserialize(serialize(obj));
+  assert(clonedObj.e instanceof DOMException);
+  assert.strictEqual(clonedObj.e.name, e.name);
+  assert.strictEqual(clonedObj.e.message, e.message);
+}