diff --git a/dev-packages/e2e-tests/test-applications/nextjs-16-streaming/tests/route-handler.test.ts b/dev-packages/e2e-tests/test-applications/nextjs-16-streaming/tests/route-handler.test.ts
index be6be4c220b7..c494ac2530d4 100644
--- a/dev-packages/e2e-tests/test-applications/nextjs-16-streaming/tests/route-handler.test.ts
+++ b/dev-packages/e2e-tests/test-applications/nextjs-16-streaming/tests/route-handler.test.ts
@@ -1,7 +1,10 @@
 import test, { expect } from '@playwright/test';
 import { waitForError, waitForStreamedSpan, getSpanOp } from '@sentry-internal/test-utils';
+import { isDevMode } from './isDevMode';
 
 test('Should create a streamed span for node route handlers', async ({ request }) => {
+  test.skip(isDevMode, 'Turbopack intermittently returns 404 for dynamic routes in dev mode');
+
   const rootSpanPromise = waitForStreamedSpan('nextjs-16-streaming', span => {
     return span.name === 'GET /route-handler/[xoxo]/node' && getSpanOp(span) === 'http.server' && span.is_segment;
   });
@@ -16,6 +19,8 @@ test('Should create a streamed span for node route handlers', async ({ request }
 });
 
 test('Should report an error linked to the correct trace for a throwing route handler', async ({ request }) => {
+  test.skip(isDevMode, 'Turbopack intermittently returns 404 for dynamic routes in dev mode');
+
   const errorEventPromise = waitForError('nextjs-16-streaming', errorEvent => {
     return errorEvent?.exception?.values?.some(value => value.value === 'route-handler-error') ?? false;
   });
@@ -37,6 +42,8 @@ test('Should report an error linked to the correct trace for a throwing route ha
 test('Should set a parameterized transaction name on a captureMessage event in a route handler', async ({
   request,
 }) => {
+  test.skip(isDevMode, 'Turbopack intermittently returns 404 for dynamic routes in dev mode');
+
   const messageEventPromise = waitForError('nextjs-16-streaming', event => {
     return event?.message === 'route-handler-message';
   });
diff --git a/dev-packages/e2e-tests/test-applications/nextjs-16-streaming/tests/server-components.test.ts b/dev-packages/e2e-tests/test-applications/nextjs-16-streaming/tests/server-components.test.ts
index ba64953678b3..4855697e7753 100644
--- a/dev-packages/e2e-tests/test-applications/nextjs-16-streaming/tests/server-components.test.ts
+++ b/dev-packages/e2e-tests/test-applications/nextjs-16-streaming/tests/server-components.test.ts
@@ -1,7 +1,10 @@
 import { expect, test } from '@playwright/test';
 import { waitForStreamedSpan, waitForStreamedSpans, getSpanOp } from '@sentry-internal/test-utils';
+import { isDevMode } from './isDevMode';
 
 test('Sends a streamed span for a request to app router with URL', async ({ page }) => {
+  test.skip(isDevMode, 'Turbopack intermittently returns 404 for nested dynamic routes in dev mode');
+
   const rootSpanPromise = waitForStreamedSpan('nextjs-16-streaming', span => {
     return span.name === 'GET /parameterized/[one]/beep/[two]' && span.is_segment;
   });
diff --git a/dev-packages/e2e-tests/test-applications/nextjs-16/tests/isDevMode.ts b/dev-packages/e2e-tests/test-applications/nextjs-16/tests/isDevMode.ts
index d2be94232110..28f60f6f035c 100644
--- a/dev-packages/e2e-tests/test-applications/nextjs-16/tests/isDevMode.ts
+++ b/dev-packages/e2e-tests/test-applications/nextjs-16/tests/isDevMode.ts
@@ -1 +1,2 @@
 export const isDevMode = !!process.env.TEST_ENV && process.env.TEST_ENV.includes('development');
+export const isTurbopackDevMode = process.env.TEST_ENV === 'development';
diff --git a/dev-packages/e2e-tests/test-applications/nextjs-16/tests/route-handler.test.ts b/dev-packages/e2e-tests/test-applications/nextjs-16/tests/route-handler.test.ts
index e37c39eb4dba..6f7de6aeb14f 100644
--- a/dev-packages/e2e-tests/test-applications/nextjs-16/tests/route-handler.test.ts
+++ b/dev-packages/e2e-tests/test-applications/nextjs-16/tests/route-handler.test.ts
@@ -1,7 +1,10 @@
 import test, { expect } from '@playwright/test';
 import { waitForError, waitForTransaction } from '@sentry-internal/test-utils';
+import { isTurbopackDevMode } from './isDevMode';
 
 test('Should create a transaction for node route handlers', async ({ request }) => {
+  test.skip(isTurbopackDevMode, 'Turbopack intermittently returns 404 for dynamic routes in dev mode');
+
   const routehandlerTransactionPromise = waitForTransaction('nextjs-16', async transactionEvent => {
     return transactionEvent?.transaction === 'GET /route-handler/[xoxo]/node';
   });
@@ -13,11 +16,7 @@ test('Should create a transaction for node route handlers', async ({ request })
 
   expect(routehandlerTransaction.contexts?.trace?.status).toBe('ok');
   expect(routehandlerTransaction.contexts?.trace?.op).toBe('http.server');
-
-  // This is flaking on dev mode
-  if (process.env.TEST_ENV !== 'development' && process.env.TEST_ENV !== 'dev-turbopack') {
-    expect(routehandlerTransaction.contexts?.trace?.data?.['http.request.header.x_charly']).toBe('gomez');
-  }
+  expect(routehandlerTransaction.contexts?.trace?.data?.['http.request.header.x_charly']).toBe('gomez');
 });
 
 test('Should create a transaction for edge route handlers', async ({ request }) => {
@@ -41,6 +40,8 @@ test('Should create a transaction for edge route handlers', async ({ request })
 test('Should report an error with a parameterized transaction name for a throwing route handler', async ({
   request,
 }) => {
+  test.skip(isTurbopackDevMode, 'Turbopack intermittently returns 404 for dynamic routes in dev mode');
+
   const errorEventPromise = waitForError('nextjs-16', errorEvent => {
     return errorEvent?.exception?.values?.some(value => value.value === 'route-handler-error') ?? false;
   });
@@ -63,23 +64,6 @@ test('Should report an error with a parameterized transaction name for a throwin
   // Error should carry the parameterized transaction name
   expect(errorEvent.transaction).toBe('GET /route-handler/[xoxo]/error');
 
-  // On turbopack (no wrapping loader), the error goes through onRequestError which sets nextjs context.
-  // On webpack, the wrapping loader's error handler fires first and captures without nextjs context.
-  // The SDK deduplicates by error identity, so only the first capture survives.
-  if (process.env.TEST_ENV === 'development') {
-    expect(errorEvent.contexts?.nextjs).toEqual({
-      route_type: 'route',
-      router_kind: 'App Router',
-      router_path: '/route-handler/[xoxo]/error',
-      request_path: '/route-handler/456/error',
-    });
-
-    expect(errorEvent.exception?.values?.[0]?.mechanism).toEqual({
-      handled: false,
-      type: 'auto.function.nextjs.on_request_error',
-    });
-  }
-
   // Transaction should have parameterized name and internal_error status
   expect(transactionEvent.transaction).toBe('GET /route-handler/[xoxo]/error');
   expect(transactionEvent.contexts?.trace?.status).toBe('internal_error');
@@ -88,6 +72,8 @@ test('Should report an error with a parameterized transaction name for a throwin
 test('Should set a parameterized transaction name on a captureMessage event in a route handler', async ({
   request,
 }) => {
+  test.skip(isTurbopackDevMode, 'Turbopack intermittently returns 404 for dynamic routes in dev mode');
+
   const messageEventPromise = waitForError('nextjs-16', event => {
     return event?.message === 'route-handler-message';
   });
@@ -119,6 +105,8 @@ test('Should set a parameterized transaction name on a captureMessage event in a
 test('Should set a parameterized transaction name on a captureException event in a route handler', async ({
   request,
 }) => {
+  test.skip(isTurbopackDevMode, 'Turbopack intermittently returns 404 for dynamic routes in dev mode');
+
   const errorEventPromise = waitForError('nextjs-16', errorEvent => {
     return errorEvent?.exception?.values?.some(value => value.value === 'route-handler-capture-exception') ?? false;
   });
diff --git a/dev-packages/e2e-tests/test-applications/nextjs-16/tests/server-components.test.ts b/dev-packages/e2e-tests/test-applications/nextjs-16/tests/server-components.test.ts
index 81aa5c98288c..b0eb803300b0 100644
--- a/dev-packages/e2e-tests/test-applications/nextjs-16/tests/server-components.test.ts
+++ b/dev-packages/e2e-tests/test-applications/nextjs-16/tests/server-components.test.ts
@@ -1,7 +1,10 @@
 import { expect, test } from '@playwright/test';
 import { waitForTransaction } from '@sentry-internal/test-utils';
+import { isTurbopackDevMode } from './isDevMode';
 
 test('Sends a transaction for a request to app router with URL', async ({ page }) => {
+  test.skip(isTurbopackDevMode, 'Turbopack intermittently returns 404 for nested dynamic routes in dev mode');
+
   const serverComponentTransactionPromise = waitForTransaction('nextjs-16', transactionEvent => {
     return (
       transactionEvent?.transaction === 'GET /parameterized/[one]/beep/[two]' &&
@@ -74,6 +77,8 @@ test('Will create a transaction with spans for every server component and metada
 test('Will create a transaction with spans for every server component and metadata generation functions when visiting a dynamic page', async ({
   page,
 }) => {
+  test.skip(isTurbopackDevMode, 'Turbopack intermittently returns 404 for dynamic routes in dev mode');
+
   const serverTransactionEventPromise = waitForTransaction('nextjs-16', async transactionEvent => {
     return transactionEvent?.transaction === 'GET /nested-layout/[dynamic]';
   });